Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | GRK5 | P34947 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29990598 | 1.00 | CNR2 (0.48) | CNR2CNR1CFTRALDH1A1GAA | |
| SCHEMBL31292480 | 0.87 | CNR2 (0.48) | CNR2CNR1CFTRALDH1A1GAA | |
| SCHEMBL730020 | 0.82 | CNR1 (0.52) | CNR2CNR1CFTRALDH1A1GAA | |
| SCHEMBL29990640 | 0.81 | CNR2 (0.48) | CNR2CNR1ALDH1A1MAPTMEN1 | |
| SCHEMBL29990602 | 0.81 | CNR2 (0.48) | CNR2CNR1CFTRGAAKCNN4 | |
| SCHEMBL730091 | 0.81 | CNR1 (0.48) | CNR2CNR1CFTRALDH1A1GAA | |
| SCHEMBL25168297 | 0.81 | CNR2 (0.48) | CNR2CNR1CFTRGAAKCNN4 | |
| SCHEMBL26095412 | 0.81 | CNR2 (0.48) | CNR2CNR1ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6978330 | 0.79 | ALDH1A1 (0.50) | CNR2CNR1CFTRALDH1A1GAA | |
| SCHEMBL23582257 | 0.79 | CNR2 (0.60) | CNR2CNR1CFTRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4177248-A1 | A CLASS OF TRICYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | Hefei Institute of Pharmaceutical Industry Co., Ltd. (CN) | 2023-05-10 | — | — | EP | disclosed |
| US-20230140276-A1 | TRICYCLIC COMPOUNDS, PREPARATION METHOD AND MEDICAL USE THEREOF | HEFEI AMVITE PHARMACEUTICAL CO., LTD. (CN) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140276-A1 | TRICYCLIC COMPOUNDS, PREPARATION METHOD AND MEDICAL USE THEREOF | HNMT, CHRM1, HRH4 | CNR2 42/4885CNR1 40/4885CFTR 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.