Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635862 | 0.80 | HPGD (0.58) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL31037128 | 0.80 | HPGD (0.58) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL18716074 | 0.74 | HPGD (0.62) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL18716135 | 0.72 | HPGD (0.59) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL31256488 | 0.72 | HPGD (0.59) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL3220975 | 0.71 | HPGD (0.58) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL7306511 | 0.71 | PIM1 (0.43) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL11539587 | 0.70 | HPGD (0.56) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL7299430 | 0.70 | HPGD (0.70) | HPGDALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL18068458 | 0.70 | HPGD (0.56) | HPGDALOX15RECQLHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |