Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207731 | 0.79 | HPGD (0.55) | PIM1SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7301115 | 0.71 | HPGD (0.46) | CDK2MAPTALOX15RECQLHSD17B10 | |
| SCHEMBL7306647 | 0.71 | SELL (0.46) | PIM1PRKACAPRKACGPRKACBATP1A1 | |
| SCHEMBL7298157 | 0.70 | PTPN22 (0.46) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL372102 | 0.67 | PIM1 (0.43) | PIM1SRCPRKACAPRKACGPRKACB | |
| SCHEMBL20356047 | 0.67 | HIF1A (0.54) | PIM1SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7299430 | 0.65 | HPGD (0.70) | PIM1CDK2MAPTALOX15RECQL | |
| SCHEMBL8408384 | 0.65 | IDO1 (0.68) | MAPTALOX15RECQLHSD17B10APP | |
| SCHEMBL3991314 | 0.65 | IDO1 (0.52) | PIM1SRCPRKACAPRKACGPRKACB | |
| SCHEMBL16641054 | 0.64 | HIF1A (0.52) | PIM1SRCPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |