Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.54 |
| ▸ | MAOB | P27338 | 9/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302703 | 0.84 | ACHE (0.60) | ACHEMAOBMAOA | |
| SCHEMBL7295471 | 0.81 | ACHE (0.56) | ACHEMAOBMAOA | |
| SCHEMBL7303013 | 0.81 | MAOB (0.58) | ACHEMAOBMAOA | |
| SCHEMBL7303830 | 0.80 | ACHE (0.55) | ACHEMAOBMAOA | |
| SCHEMBL5617681 | 0.76 | MAOB (0.53) | ACHEMAOBMAOA | |
| SCHEMBL5618346 | 0.76 | MAOB (0.53) | ACHEMAOBMAOA | |
| SCHEMBL7295636 | 0.76 | MAOB (0.53) | ACHEMAOBMAOA | |
| SCHEMBL5618127 | 0.75 | MAOB (0.52) | ACHEMAOBMAOA | |
| SCHEMBL7300837 | 0.75 | ACHE (0.63) | ACHEMAOBMAOA | |
| SCHEMBL7294468 | 0.75 | ACHE (0.63) | ACHEMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363796-B1 | HETEROCYCLICALLY SUBSTITUTED ALKOXYCOUMARINES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5227392-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5073563-A | Enzyme inhibitors, CNS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |
| EP-0363796-A1 | Heterocyclically substituted alkoxycoumarines, method for their preparation and therapeutical agents containing same | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |