Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.60 |
| ▸ | MAOB | P27338 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303013 | 0.86 | MAOB (0.58) | ACHEMAOBMAOA | |
| SCHEMBL7301127 | 0.84 | ACHE (0.54) | ACHEMAOBMAOA | |
| SCHEMBL7300837 | 0.80 | ACHE (0.63) | ACHEMAOBMAOA | |
| SCHEMBL7294468 | 0.80 | ACHE (0.63) | ACHEMAOBMAOA | |
| SCHEMBL7301295 | 0.79 | ACHE (0.62) | ACHEMAOBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7301364 | 0.78 | MAOB (0.66) | ACHEMAOBHSD17B10MAOA | |
| SCHEMBL7301269 | 0.77 | ACHE (0.78) | ACHEMAOBMAOA | |
| SCHEMBL7295468 | 0.76 | ACHE (0.58) | ACHEMAOBCYP2C9CYP2C19MAOA | |
| SCHEMBL26743702 | 0.76 | HPGD (0.78) | ACHEMAOBCYP2C9CYP2C19MAOA | |
| SCHEMBL7432074 | 0.76 | ACHE (1.00) | ACHEMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363796-B1 | HETEROCYCLICALLY SUBSTITUTED ALKOXYCOUMARINES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5227392-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5073563-A | Enzyme inhibitors, CNS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |
| EP-0363796-A1 | Heterocyclically substituted alkoxycoumarines, method for their preparation and therapeutical agents containing same | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |