Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL324618 | 0.90 | ALDH1A1 (0.35) | MEN1POLBKMT2AALDH1A1 | |
| Ether SCHEMBL7862995 | 0.84 | ALDH1A1 (0.38) | MEN1POLBKMT2AALDH1A1 | |
| Cyclohexane SCHEMBL8471239 | 0.83 | ADH1C (0.32) | KMT2AALDH1A1 | |
| Cyclohexane SCHEMBL7376420 | 0.83 | ALDH1A1 (0.39) | ALDH1A1 | |
| Cyclopentane SCHEMBL8923462 | 0.83 | ALDH1A1 (0.39) | ALDH1A1 | |
| Cyclohexane SCHEMBL8441380 | 0.83 | ALDH1A1 (0.39) | ALDH1A1 | |
| Cyclohexane SCHEMBL2292997 | 0.83 | ALDH1A1 (0.39) | ALDH1A1 | |
| Cyclohexane SCHEMBL2297628 | 0.83 | ALDH1A1 (0.39) | ALDH1A1 | |
| Ether SCHEMBL232500 | 0.83 | — | — | |
| Cyclohexane SCHEMBL8441382 | 0.83 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861414-A | INHIBITING BLOOD PLATELET AGGREGATION FOR ANTITHROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1999-01-19 | — | — | US | disclosed |
| EP-0501322-B1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LTD (GB) | 1996-09-04 | — | — | EP | disclosed |
| WO-1992014727-A1 | 3-PIPERIDINYLMETHYLCARBOXYLATE SUBSTITUTED INDOLES | GLAXO GROUP LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |
| EP-0501322-A1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LIMITED (GB) | 1992-09-02 | — | — | EP | disclosed |