Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.70 |
| ▸ | ACHE | P22303 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302123 | 0.87 | MAOB (0.77) | MAOBACHEMAOA | |
| Atibeprone SCHEMBL2111018 | 0.82 | MAOB (1.00) | MAOBACHEMAOA | |
| SCHEMBL5617596 | 0.81 | MAOB (0.67) | MAOBACHEKDM4EMAOA | |
| SCHEMBL26743702 | 0.80 | HPGD (0.78) | MAOBACHEKDM4EALDH1A1GAA | |
| SCHEMBL7291407 | 0.80 | MAOB (0.64) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL7294868 | 0.80 | MAOB (0.64) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL7293827 | 0.79 | MAOB (0.65) | MAOBACHEKDM4EALDH1A1GAA | |
| SCHEMBL7294468 | 0.76 | ACHE (0.63) | MAOBACHEMAOA | |
| SCHEMBL7300706 | 0.76 | ACHE (0.66) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL7296443 | 0.74 | ALDH1A1 (0.64) | MAOBKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363796-B1 | HETEROCYCLICALLY SUBSTITUTED ALKOXYCOUMARINES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5227392-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5073563-A | Enzyme inhibitors, CNS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |
| EP-0363796-A1 | Heterocyclically substituted alkoxycoumarines, method for their preparation and therapeutical agents containing same | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |