⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545760 | 0.80 | — | — | |
| SCHEMBL4029052 | 0.74 | — | — | |
| SCHEMBL2874226 | 0.74 | — | — | |
| SCHEMBL7469530 | 0.70 | — | — | |
| SCHEMBL6202808 | 0.69 | HRH3 (0.30) | — | |
| SCHEMBL4434374 | 0.69 | — | — | |
| SCHEMBL18373133 | 0.69 | — | — | |
| SCHEMBL1477282 | 0.66 | TAAR1 (0.34) | — | |
| SCHEMBL8924494 | 0.64 | KEAP1 (0.38) | — | |
| SCHEMBL15409910 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130735-B2 | Process for the preparation of fluopicolide | BAYER AKTIENGESELLSCHAFT | 2021-09-28 | — | — | US | claimed |
| EP-3713917-A1 | PROCESS FOR THE PREPARATION OF FLUOPICOLIDE | Bayer Aktiengesellschaft (DE) | 2020-09-30 | — | — | EP | claimed |
| US-20200283388-A1 | PROCESS FOR THE PREPARATION OF FLUOPICOLIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2020-09-10 | — | — | US | claimed |
| WO-2019101769-A1 | PROCESS FOR THE PREPARATION OF FLUOPICOLIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2019-05-31 | — | — | WO | claimed |
| EP-3489221-A1 | PROCESS FOR THE PREPARATION OF FLUOPICOLIDE | Bayer AG (DE) | 2019-05-29 | — | — | EP | claimed |
| US-6417195-B1 | LIBRARIES AND COMBINATORIAL CHEMISTRY | LION BIOSCIENCE AG (DE) | 2002-07-09 | — | — | US | claimed |
| EP-0863877-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INST (US) | 1999-07-21 | — | — | EP | claimed |
| US-5916899-A | SOLID PHASE SYNTHESIS, REACTING PROTECTED AMINO ACID WITH SOLID SUPPORT; FORMING IMINE BY REACTION WITH ALDEHYDE, CYCLIZATION WITH ANHYDRIDE, CLEAVAGE AND DEPROTECTION. | TREGA BIOSCIENCES, INC. (US) | 1999-06-29 | — | — | US | claimed |
| US-5874443-A | BIOSYNTHESIS | TREGA BIOSCIENCES, INC. (US) | 1999-02-23 | — | — | US | claimed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| EP-0413750-A1 | RENIN INHIBITORY PEPTIDES CONTAINING A SUBSTITUTED PHENOXYACETYLE GROUP | THE UPJOHN COMPANY (US) | 1991-02-27 | — | — | EP | claimed |
| WO-1989010920-A1 | RENIN INHIBITORY PEPTIDES CONTAINING A SUBSTITUTED PHENOXYACETYLE GROUP | THE UPJOHN COMPANY (US) | 1989-11-16 | — | — | WO | claimed |
| US-11130735-B2 | Process for the preparation of fluopicolide | BAYER AKTIENGESELLSCHAFT | 2021-09-28 | — | — | US | disclosed |
| EP-3713917-A1 | PROCESS FOR THE PREPARATION OF FLUOPICOLIDE | Bayer Aktiengesellschaft (DE) | 2020-09-30 | — | — | EP | disclosed |
| US-20200283388-A1 | PROCESS FOR THE PREPARATION OF FLUOPICOLIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2020-09-10 | — | — | US | disclosed |
| WO-1987005909-A2 | RENIN INHIBITORS HAVING A LACTAM PSEUDO DIPEPTIDE | THE UPJOHN COMPANY (US) | 1987-10-08 | — | — | WO | disclosed |
| EP-0237202-A2 | Novel renin inhibiting peptides having a dihydroxyethylene isostere transition state insert | THE UPJOHN COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| WO-1987005302-A1 | NOVEL RENIN-INHIBITING PEPTIDES HAVING A DIHYDROXYETHYLENE ISOSTERE TRANSITION STATE INSERT | THE UPJOHN COMPANY (US) | 1987-09-11 | — | — | WO | disclosed |
| EP-0173481-A2 | Peptides | THE UPJOHN COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |