Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | PTEN | P60484 | 1/20 | 0.32 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469530 | 0.70 | — | — | |
| SCHEMBL8924767 | 0.68 | APEX1 (0.38) | NPSR1HSD17B10CDC25ACDC25BMAPK1 | |
| SCHEMBL28396603 | 0.64 | — | — | |
| SCHEMBL7301173 | 0.64 | — | — | |
| Succinic Acid SCHEMBL2578311 | 0.61 | LMNA (0.50) | NR4A2HDAC3MAPK1HDAC1HDAC2 | |
| SCHEMBL28737712 | 0.60 | NPSR1 (0.54) | KEAP1FFAR1NPSR1CHRM1PTGER1 | |
| SCHEMBL5670212 | 0.58 | KEAP1 (0.64) | KEAP1FFAR1NPSR1FFAR4PTPRB | |
| SCHEMBL69746 | 0.58 | FFAR1 (0.81) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| Succinic Acid SCHEMBL30394694 | 0.57 | LMNA (0.90) | NPSR1CYP1A2HSD17B10HDAC3MAPK1 | |
| SCHEMBL23829749 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |