Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301191 | 1.00 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL27568108 | 0.91 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7307644 | 0.83 | MAPT (0.63) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7307640 | 0.83 | MAPT (0.63) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL5368158 | 0.82 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL27525127 | 0.82 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7306019 | 0.80 | HTT (0.70) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7306010 | 0.80 | HTT (0.70) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL16599448 | 0.79 | KMT2A (0.89) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL4456981 | 0.79 | KMT2A (0.89) | RAB9ANPC1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |