Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306377 | 0.94 | ITGB3 (0.40) | ITGB3ITGA2BMCHR1DRD2DRD3 | |
| SCHEMBL7301374 | 0.91 | ITGB3 (0.50) | ITGB3ITGA2BLMNA | |
| SCHEMBL7307568 | 0.86 | ALDH1A1 (0.38) | ITGB3ITGA2BMCHR1DRD2DRD3 | |
| SCHEMBL7311321 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7392906 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7392479 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL7301234 | 0.84 | ITGB3 (0.36) | ITGB3ITGA2BLMNAMCHR1 | |
| SCHEMBL7395082 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7398673 | 0.82 | ITGB3 (0.55) | ITGB3ITGA2BLMNAMCHR1 | |
| SCHEMBL7303273 | 0.81 | MCHR1 (0.45) | ITGB3ITGA2BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |