Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | ACHE | P22303 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302386 | 0.91 | MAOB (0.58) | MAOBACHEMAOA | |
| SCHEMBL7302076 | 0.85 | MAOB (0.61) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL7303229 | 0.80 | TDP1 (0.60) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL7303152 | 0.80 | ACHE (0.59) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL7305804 | 0.80 | MAOB (0.44) | MAOBACHEMAOA | |
| SCHEMBL5617560 | 0.79 | MAOB (0.45) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL7304086 | 0.79 | SLC26A3 (0.43) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL7440445 | 0.77 | MAOB (0.63) | MAOBACHEMAOA | |
| SCHEMBL7303132 | 0.75 | MAOB (0.43) | MAOBACHEALDH1A1HSD17B10 | |
| SCHEMBL7302120 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363796-B1 | HETEROCYCLICALLY SUBSTITUTED ALKOXYCOUMARINES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5227392-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5073563-A | Enzyme inhibitors, CNS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |
| EP-0363796-A1 | Heterocyclically substituted alkoxycoumarines, method for their preparation and therapeutical agents containing same | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |