Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | GPR4 | P46093 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21083686 | 0.81 | GPR4 (0.53) | GPR4 | |
| SCHEMBL242856 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL4329804 | 0.75 | GPR4 (0.52) | AGTR1AGTR2GPR4 | |
| SCHEMBL4329809 | 0.75 | GPR4 (0.52) | AGTR1AGTR2GPR4 | |
| SCHEMBL7422797 | 0.75 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL7298948 | 0.75 | AGTR1 (0.49) | AGTR1AGTR2GPR4 | |
| Potassium SCHEMBL8826225 | 0.74 | AGTR1 (0.49) | AGTR1AGTR2GPR4 | |
| SCHEMBL8826204 | 0.74 | AGTR1 (0.49) | AGTR1AGTR2GPR4 | |
| SCHEMBL7842068 | 0.73 | — | — | |
| SCHEMBL7300425 | 0.73 | AGTR1 (0.44) | AGTR1AGTR2GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594010-A | TREATMENT OF HYPERTENSION AND ATHERIOSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| EP-0630896-A1 | Substituted mono- and bipyridylmethyl derivatives as angiotensin II antagonist | BAYER AG (DE) | 1994-12-28 | — | — | EP | disclosed |