Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301363 | 1.00 | FKBP1A (0.47) | FKBP1AATMMEN1KMT2APOLB | |
| SCHEMBL7305475 | 0.96 | FKBP1A (0.53) | FKBP1AF2DPP4ITGB1ITGA4 | |
| SCHEMBL7305485 | 0.96 | FKBP1A (0.53) | FKBP1AF2DPP4ITGB1ITGA4 | |
| SCHEMBL7309531 | 0.95 | FKBP1A (0.51) | FKBP1AF2EBPSIGMAR1ITGB1 | |
| SCHEMBL7309517 | 0.95 | FKBP1A (0.51) | FKBP1AF2EBPSIGMAR1ITGB1 | |
| SCHEMBL7316073 | 0.92 | DPP4 (0.48) | FKBP1AATMMEN1KMT2APOLB | |
| SCHEMBL7316065 | 0.92 | DPP4 (0.48) | FKBP1AATMMEN1KMT2APOLB | |
| SCHEMBL7310783 | 0.92 | CYP3A4 (0.42) | FKBP1AATMMEN1KMT2APOLB | |
| SCHEMBL7310776 | 0.92 | CYP3A4 (0.42) | FKBP1AATMMEN1KMT2APOLB | |
| SCHEMBL7306032 | 0.92 | F2 (0.49) | FKBP1APOLBF2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |