Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292683 | 0.89 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2PPARDPPARA | |
| SCHEMBL11199479 | 0.82 | NR1H4 (0.54) | RAB9ANPC1SMN1; SMN2MAPTNR1H4 | |
| SCHEMBL18466548 | 0.82 | PPARD (0.65) | RAB9ANPC1SMN1; SMN2PPARDPPARA | |
| SCHEMBL31553815 | 0.81 | NPC1 (0.49) | RAB9ANPC1SMN1; SMN2MAPTS1PR1 | |
| SCHEMBL10934713 | 0.80 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL31014722 | 0.80 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2PPARDPPARA | |
| SCHEMBL12490994 | 0.78 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL5661097 | 0.75 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL22135769 | 0.74 | MAPT (0.58) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL6328330 | 0.74 | PPARD (0.56) | RAB9ANPC1PPARDPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |