Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978731 | 0.85 | HTT (0.62) | SMN1; SMN2TSHRMAPK1L3MBTL1NR1H4 | |
| SCHEMBL11199479 | 0.84 | NR1H4 (0.54) | SMN1; SMN2L3MBTL1NR1H4NOTUMNPC1 | |
| SCHEMBL31553815 | 0.83 | NPC1 (0.49) | SMN1; SMN2TSHRMAPK1L3MBTL1S1PR1 | |
| SCHEMBL1544450 | 0.82 | MAPT (0.54) | SMN1; SMN2TSHRL3MBTL1NPSR1NPC1 | |
| SCHEMBL30268662 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRMAPK1L3MBTL1NR1H4 | |
| Hydrochloric Acid SCHEMBL29485503 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRMAPK1L3MBTL1NR1H4 | |
| SCHEMBL7301479 | 0.80 | RAB9A (0.57) | SMN1; SMN2TSHRMAPK1L3MBTL1NR1H4 | |
| SCHEMBL21900753 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRMAPK1L3MBTL1NR1H4 | |
| SCHEMBL9963719 | 0.79 | S1PR1 (0.60) | SMN1; SMN2TSHRMAPK1L3MBTL1NR1H4 | |
| SCHEMBL19091431 | 0.77 | S1PR1 (0.61) | SMN1; SMN2TSHRMAPK1L3MBTL1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300932-A1 | N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | GUIZHOU UNIVERSITY (CN) | 2024-09-12 | — | — | US | disclosed |
| CN-116731003-A | N-phenylimine-containing derivative, and preparation method and application thereof | 贵州大学 | 2023-09-12 | — | — | CN | disclosed |
| US-4497804-A | Insecticidal, acaricidal, and nematicidal O-ethyl S-alkyl S-(1,2,4-oxadiazol-5-yl-methyl) phosphorodithiolate derivatives, compositions, and methods of use | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-02-05 | — | — | US | disclosed |
| EP-0081151-A1 | Organophosphates, process for preparing them and pesticides containing them | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300932-A1 | N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | PNMT, NNMT, PAH | SMN1; SMN2 1700/4885TSHR 4062/4885MAPK1 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.