Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 11/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294861 | 1.00 | PREP (0.39) | PREPADRA1DADRA1AADRA1BNPY1R | |
| SCHEMBL7295266 | 1.00 | PREP (0.39) | PREPADRA1DADRA1AADRA1BNPY1R | |
| SCHEMBL7296404 | 0.92 | GAA (0.36) | PREPMME | |
| SCHEMBL7293757 | 0.89 | GBA1 (0.38) | PREPADRA1DADRA1AADRA1BNPY1R | |
| SCHEMBL7293977 | 0.87 | GAA (0.33) | PREP | |
| SCHEMBL7301359 | 0.86 | ITGB3 (0.37) | NPY1RNPY5RDGAT1 | |
| SCHEMBL8155778 | 0.85 | PREP (0.36) | PREPADRA1DADRA1AADRA1BNPY1R | |
| SCHEMBL7305086 | 0.85 | ADRA1D (0.39) | PREPADRA1DADRA1AADRA1BNPY1R | |
| SCHEMBL7302246 | 0.85 | PREP (0.54) | PREP | |
| SCHEMBL7302057 | 0.85 | ADRA1D (0.39) | PREPADRA1DADRA1AADRA1BNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017929-A | Cholinesterase activator | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0754454-A1 | CHOLINESTERASE ACTIVATOR | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |