Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301585 | 1.00 | LMNA (0.50) | LMNAPOLBF2SMN1; SMN2HRH3 | |
| SCHEMBL29416795 | 0.82 | LMNA (0.55) | LMNAPOLBF2SMN1; SMN2HRH3 | |
| SCHEMBL7289930 | 0.82 | LMNA (0.55) | LMNAPOLBF2SMN1; SMN2HRH3 | |
| SCHEMBL7304558 | 0.82 | LMNA (0.49) | LMNAPOLBF2SMN1; SMN2HRH3 | |
| SCHEMBL7306911 | 0.76 | F2 (0.48) | POLBF2SMN1; SMN2 | |
| SCHEMBL7306906 | 0.76 | F2 (0.48) | POLBF2SMN1; SMN2 | |
| SCHEMBL7306914 | 0.76 | F2 (0.48) | POLBF2SMN1; SMN2 | |
| SCHEMBL7291612 | 0.75 | LMNA (0.52) | LMNAPOLBSMN1; SMN2HRH3DPP4 | |
| SCHEMBL7301151 | 0.74 | MEN1 (0.48) | F2 | |
| SCHEMBL7301163 | 0.74 | MEN1 (0.48) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | claimed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |