Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291612 | 0.83 | LMNA (0.52) | LMNASMN1; SMN2POLBDPP4DPP8 | |
| SCHEMBL7301585 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2POLBDPP4DPP8 | |
| SCHEMBL7301582 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2POLBDPP4DPP8 | |
| SCHEMBL7297403 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2POLBDPP4DPP8 | |
| SCHEMBL29416795 | 0.75 | LMNA (0.55) | LMNASMN1; SMN2POLBF2HRH3 | |
| SCHEMBL7289930 | 0.75 | LMNA (0.55) | LMNASMN1; SMN2POLBF2HRH3 | |
| SCHEMBL7307176 | 0.74 | PREP (0.57) | DPP4DPP8DPP7ALDH1A1KMT2A | |
| SCHEMBL7283244 | 0.73 | CYP3A4 (0.48) | LMNADPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL1804892 | 0.73 | LMNA (0.55) | LMNASMN1; SMN2POLBDPP4DPP8 | |
| SCHEMBL1237539 | 0.73 | LMNA (0.55) | LMNASMN1; SMN2POLBDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |