Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.79 |
| ▸ | HTR2A | P28223 | 1/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.79 |
| ▸ | HRH1 | P35367 | 1/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7280934 | 0.98 | HTR3A (0.76) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| SCHEMBL7291599 | 0.89 | HTR3A (0.80) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Azasetron SCHEMBL13186328 | 0.88 | HTR3A (1.00) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Azasetron SCHEMBL19492326 | 0.88 | HTR3A (1.00) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Azasetron SCHEMBL29880168 | 0.88 | HTR3A (1.00) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Hydrochloric Acid SCHEMBL7291727 | 0.88 | HTR3A (0.79) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Azasetron SCHEMBL17191 | 0.88 | HTR3A (1.00) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Azasetron SCHEMBL19463750 | 0.88 | HTR3A (1.00) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Azasetron SCHEMBL17190 | 0.88 | HTR3A (1.00) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Azasetron SCHEMBL442156 | 0.87 | HTR3A (0.98) | HTR3AHTR2ASLC6A4HRH1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |