Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 7/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292000 | 0.92 | PREP (0.34) | PREPHTR1AHTR2AHTR7HTR6 | |
| SCHEMBL7293303 | 0.81 | PREP (0.46) | PREPHTR1AHTR2AHTR7HTR6 | |
| SCHEMBL7429471 | 0.74 | PREP (0.44) | PREPHTR1AHTR2AHTR7HTR6 | |
| SCHEMBL7436192 | 0.72 | PREP (0.45) | PREP | |
| SCHEMBL7292436 | 0.72 | PREP (0.57) | PREP | |
| SCHEMBL7359542 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL7301136 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL7304535 | 0.66 | PREP (0.60) | PREP | |
| SCHEMBL7435975 | 0.66 | PREP (0.59) | PREP | |
| SCHEMBL7294659 | 0.65 | PREP (0.55) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |