Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728630 | 0.97 | IDO1 (0.46) | IDO1ANPEPPLAU | |
| SCHEMBL73467 | 0.97 | IDO1 (0.46) | IDO1ANPEPPLAU | |
| Hydrochloric Acid SCHEMBL4151874 | 0.94 | ANPEP (0.48) | IDO1ANPEPPLAU | |
| Methyl Alcohol SCHEMBL28162178 | 0.92 | IDO1 (0.42) | IDO1ANPEPPLAU | |
| Ammonia Solution, Strong SCHEMBL6107709 | 0.83 | ANPEP (0.55) | ANPEPPLAU | |
| Dioxane SCHEMBL3940644 | 0.83 | ANPEP (0.41) | IDO1ANPEPPLAU | |
| SCHEMBL291460 | 0.79 | ANPEP (0.57) | ANPEPPLAU | |
| SCHEMBL2943529 | 0.79 | ANPEP (0.57) | ANPEPPLAU | |
| SCHEMBL6951241 | 0.79 | ANPEP (0.57) | ANPEPPLAU | |
| SCHEMBL13998125 | 0.79 | ANPEP (0.57) | ANPEPPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828848-B1 | PREPARATION OF HYDROXY COMPOUNDS BY BIOCONVERSION WITH DIOXYGENASE | AVECIA LTD (GB) | 2002-03-27 | — | — | EP | disclosed |
| US-6087137-A | PREPARING OPTICALLY ACTIVE COMPOUNDS FOR USE AS CHEMICAL INTERMEDIATES IN SYNTHESIS OF DRUGS AND AGRICULTURAL CHEMICALS ESPECIALLY ENZYME INHIBITORS TARGETED TO HUMAN IMMUNODEFICIENCY VIRUS | ZENECA LIMITED (GB) | 2000-07-11 | — | — | US | disclosed |
| CN-1184464-A | synthesis of optically active aminoindanol | BASF AG (DE) | 1998-06-10 | — | — | CN | disclosed |
| EP-0828848-A1 | PREPARATION OF HYDROXY COMPOUNDS BY BIOCONVERSION WITH DIOXYGENASE | ZENECA LIMITED (GB) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037628-A1 | PREPARATION OF HYDROXY COMPOUNDS BY BIOCONVERSION WITH DIOXYGENASE | ZENECA LIMITED (GB) | 1996-11-28 | — | — | WO | disclosed |
| EP-0534511-A1 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0337714-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1989-10-18 | — | — | EP | disclosed |