SCHEMBL7301732

SCHEMBL7301732

CCCCc1nc(COC)c(C(=O)O)n1Cc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.66
AGTR2 P50052 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910813 0.94 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL7298585 0.92 AGTR1 (0.72) AGTR1AGTR2
SCHEMBL7300566 0.90 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL7907661 0.87 AGTR1 (0.67) AGTR1AGTR2
SCHEMBL7314316 0.86 AGTR1 (0.68) AGTR1AGTR2
SCHEMBL708 0.85 AGTR1 (0.80) AGTR1AGTR2
SCHEMBL513 0.85 AGTR1 (0.82) AGTR1AGTR2
SCHEMBL9468705 0.84 AGTR1 (0.78) AGTR1AGTR2
SCHEMBL9339135 0.84 AGTR1 (0.81) AGTR1AGTR2
SCHEMBL9427457 0.84 AGTR1 (0.64) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503785-A1 1-Biphenylimidazole derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1992-09-16 EP disclosed