SCHEMBL7300566

SCHEMBL7300566

CCCCc1nc(COC)c(C(=O)O)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.54
AGTR2 P50052 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7301745 0.94 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL7312098 0.93 ACHE (0.51)
SCHEMBL7301732 0.90 AGTR1 (0.66) AGTR1AGTR2
SCHEMBL7301771 0.89 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL7305298 0.88 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL7311709 0.87 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL7300493 0.86 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL7307641 0.86 PPARG (0.54) AGTR1AGTR2
SCHEMBL7304653 0.86 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL7910813 0.86 AGTR1 (0.62) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503785-A1 1-Biphenylimidazole derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1992-09-16 EP disclosed