Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256546 | 1.00 | TSHR (0.41) | TSHRLMNAGABRR1GABRR2BLM | |
| SCHEMBL7301833 | 1.00 | TSHR (0.41) | TSHRLMNAGABRR1GABRR2BLM | |
| SCHEMBL26293756 | 0.98 | HTT (0.42) | TSHRLMNAGABRR1GABRR2BLM | |
| SCHEMBL10455025 | 0.98 | HTT (0.42) | TSHRLMNAGABRR1GABRR2BLM | |
| SCHEMBL27733052 | 0.95 | TSHR (0.41) | TSHRLMNAGABRR1GABRR2BLM | |
| SCHEMBL3654341 | 0.91 | — | — | |
| SCHEMBL3654343 | 0.91 | — | — | |
| SCHEMBL9689980 | 0.80 | ALOX5 (0.32) | KMT2AALOX5 | |
| SCHEMBL9689986 | 0.80 | ALOX5 (0.32) | KMT2AALOX5 | |
| SCHEMBL29218708 | 0.79 | GABRR1 (0.35) | TSHRLMNAGABRR1GABRR2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601731-B | Synthesis of cyclopentenone | 陶氏环球技术有限责任公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-112638923-A | Synthesis of substituted cyclopentadiene compounds and metallocenes | 陶氏环球技术有限责任公司 | 2021-04-09 | — | — | CN | disclosed |
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | disclosed |