Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689986 | 1.00 | ALOX5 (0.32) | ALOX5EPHX1HPGDKMT2APTGS1 | |
| SCHEMBL7301835 | 0.80 | TSHR (0.41) | ALOX5KMT2A | |
| SCHEMBL29256546 | 0.80 | TSHR (0.41) | ALOX5KMT2A | |
| SCHEMBL7301833 | 0.80 | TSHR (0.41) | ALOX5KMT2A | |
| SCHEMBL25762239 | 0.79 | CTSK (0.34) | — | |
| SCHEMBL6064767 | 0.78 | — | — | |
| SCHEMBL26293756 | 0.78 | HTT (0.42) | ALOX5EPHX1HPGDKMT2AADH1B | |
| SCHEMBL10455025 | 0.78 | HTT (0.42) | ALOX5EPHX1HPGDKMT2AADH1B | |
| SCHEMBL1081814 | 0.78 | HPGD (0.38) | EPHX1HPGD | |
| SCHEMBL18507669 | 0.78 | HPGD (0.38) | EPHX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195053-B1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-02-12 | — | — | EP | disclosed |
| EP-0195053-A1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR. | CHEVRON RES & TECH (US) | 1986-09-24 | — | — | EP | disclosed |
| WO-1986002065-A1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR | CHEVRON RESEARCH COMPANY (US) | 1986-04-10 | — | — | WO | disclosed |