SCHEMBL7301839

SCHEMBL7301839

Cc1c(C)c2ccc(OCc3cccnc3)cc2oc1=O

nearest known ligand 0.75

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 15/20 0.75
ACHE P22303 14/20 0.75
MAOA P21397 4/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7432074 0.86 ACHE (1.00) MAOBACHEMAOA
SCHEMBL7301269 0.85 ACHE (0.78) MAOBACHEMAOA
SCHEMBL5617624 0.82 MAOB (1.00) MAOBACHEMAOA
SCHEMBL5618607 0.81 MAOB (1.00) MAOBACHEMAOA
SCHEMBL7428885 0.81 MAOB (1.00) MAOBACHEMAOA
SCHEMBL5617511 0.80 MAOB (0.82) MAOBACHEMAOA
SCHEMBL15585980 0.79 RAB9A (0.77) MAOBACHE
SCHEMBL7297397 0.79 ACHE (0.69) MAOBACHEMAOA
SCHEMBL5618373 0.79 ACHE (0.77) MAOBACHEMAOA
SCHEMBL7436182 0.79 MAOB (1.00) MAOBACHEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0363796-B1 HETEROCYCLICALLY SUBSTITUTED ALKOXYCOUMARINES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING SAME BASF Aktiengesellschaft (DE) 1993-08-11 EP disclosed
US-5227392-A Monoamine oxidase inhibitors BASF AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
US-5073563-A Enzyme inhibitors, CNS BASF AKTIENGESELLSCHAFT (DE) 1991-12-17 US disclosed
EP-0363796-A1 Heterocyclically substituted alkoxycoumarines, method for their preparation and therapeutical agents containing same BASF Aktiengesellschaft (DE) 1990-04-18 EP disclosed