Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9273383 | 0.99 | NR1H4 (0.47) | EPHX2NR1H4HDAC1HDAC6HTT | |
| SCHEMBL7303178 | 0.91 | MEN1 (0.52) | NPC1RAB9AMEN1KMT2ANAMPT | |
| Hydrochloric Acid SCHEMBL9275424 | 0.89 | MAPT (0.51) | NPC1RAB9AMEN1KMT2ANAMPT | |
| SCHEMBL7303517 | 0.86 | NR1H4 (0.61) | EPHX2NR1H4HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL9264373 | 0.85 | NR1H4 (0.60) | EPHX2NR1H4HDAC1HDAC6 | |
| SCHEMBL9452083 | 0.84 | EPHX2 (0.52) | EPHX2NR1H4HDAC1HDAC6HTT | |
| Hydrochloric Acid SCHEMBL9270874 | 0.83 | EPHX2 (0.51) | EPHX2NR1H4HDAC1HDAC6HTT | |
| SCHEMBL11428355 | 0.81 | KMT2A (0.47) | EPHX2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL7294446 | 0.81 | EPHX2 (0.52) | EPHX2NR1H4HDAC1HDAC6HTT | |
| SCHEMBL17894494 | 0.79 | HDAC1 (0.59) | EPHX2NR1H4HDAC1HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |