Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | ESRRG | P62508 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ESRRB | O95718 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9275424 | 0.99 | MAPT (0.51) | MEN1KMT2AMAPTNAMPTCA1 | |
| SCHEMBL7301840 | 0.91 | EPHX2 (0.48) | MEN1KMT2AMAPTNAMPTGAA | |
| Hydrochloric Acid SCHEMBL9273383 | 0.89 | NR1H4 (0.47) | MEN1KMT2AMAPTNAMPTGAA | |
| SCHEMBL7303344 | 0.88 | ST14 (0.59) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL7303034 | 0.86 | NR1H4 (0.54) | MEN1KMT2AMAPTNAMPTCA1 | |
| Hydrochloric Acid SCHEMBL9272571 | 0.86 | ST14 (0.58) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL7299564 | 0.86 | MAPT (0.57) | MEN1KMT2AMAPTNAMPTRAB9A | |
| Acetic Acid SCHEMBL9274585 | 0.84 | MAPT (0.57) | MEN1KMT2AMAPTNAMPTCA1 | |
| SCHEMBL11428355 | 0.81 | KMT2A (0.47) | MEN1KMT2AMAPTGAA | |
| SCHEMBL7295673 | 0.79 | MAPT (0.59) | MEN1KMT2AMAPTNAMPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |