Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292938 | 0.88 | MAOB (0.67) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL9136950 | 0.77 | MAOB (0.42) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL7302123 | 0.75 | MAOB (0.77) | MAOBACHEMAOA | |
| SCHEMBL7296443 | 0.74 | ALDH1A1 (0.64) | MAOBALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7304856 | 0.74 | MAOB (0.48) | MAOBALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL7293827 | 0.72 | MAOB (0.65) | MAOBALDH1A1HPGDUSP2ACHE | |
| SCHEMBL7294868 | 0.71 | MAOB (0.64) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL7291407 | 0.71 | MAOB (0.64) | MAOBALDH1A1HPGDACHEMAOA | |
| SCHEMBL7297386 | 0.70 | AR (0.66) | MAOB | |
| SCHEMBL7300401 | 0.70 | TDP1 (0.62) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0594036-A1 | Arylalkyloxythiocoumarines, process for their preparation and therapeutical agents containing them | BASF Aktiengesellschaft (DE) | 1994-04-27 | — | — | EP | disclosed |