Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300401 | 0.88 | TDP1 (0.62) | MAOBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7296443 | 0.78 | ALDH1A1 (0.64) | MAOBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7302123 | 0.76 | MAOB (0.77) | MAOB | |
| SCHEMBL7301973 | 0.74 | MAOB (0.51) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7293827 | 0.73 | MAOB (0.65) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7291407 | 0.72 | MAOB (0.64) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7314399 | 0.72 | MAOB (0.55) | MAOBALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7294868 | 0.72 | MAOB (0.64) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7308829 | 0.72 | MAOB (0.53) | MAOBKDM4EMAPT | |
| SCHEMBL7297386 | 0.71 | AR (0.66) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0594036-A1 | Arylalkyloxythiocoumarines, process for their preparation and therapeutical agents containing them | BASF Aktiengesellschaft (DE) | 1994-04-27 | — | — | EP | disclosed |