Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 8/20 | 0.47 |
| ▸ | PLG | P00747 | 4/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304387 | 0.83 | ACE (0.46) | ACEF2PLGCTRB1CASP1 | |
| SCHEMBL7302617 | 0.82 | ACE (0.45) | ACEF2FKBP1A | |
| Hydrochloric Acid SCHEMBL9226349 | 0.82 | F2 (0.52) | ACEF2PLGF10PRSS1 | |
| SCHEMBL7324515 | 0.79 | ACE (0.46) | ACEF2FKBP1A | |
| Hydrochloric Acid SCHEMBL7303227 | 0.78 | ACE (0.41) | ACEF2FKBP1A | |
| SCHEMBL7295927 | 0.75 | F2 (0.49) | ACEF2PLGF10PRSS1 | |
| Hydrochloric Acid SCHEMBL7292795 | 0.75 | F2 (0.57) | ACEF2PLGF10PRSS1 | |
| SCHEMBL7304353 | 0.73 | ACE (0.49) | ACEF2CTRB1FKBP1A | |
| SCHEMBL7295492 | 0.73 | F2 (0.43) | F2CASP1 | |
| Hydrochloric Acid SCHEMBL7294482 | 0.71 | F2 (0.47) | ACEF2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |