Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295927 | 0.93 | F2 (0.49) | ACEF2FKBP1APLGCASP1 | |
| SCHEMBL7304353 | 0.90 | ACE (0.49) | ACEF2FKBP1APRCPCTRB1 | |
| SCHEMBL7297974 | 0.86 | ACE (0.42) | ACEF2PLGCASP1PRCP | |
| SCHEMBL7302872 | 0.86 | ACE (0.44) | ACEF2FKBP1APLGCASP1 | |
| Hydrochloric Acid SCHEMBL9226349 | 0.85 | F2 (0.52) | ACEF2FKBP1APLG | |
| SCHEMBL7294595 | 0.83 | KMT2A (0.45) | ACEF2PLGCASP1PRCP | |
| SCHEMBL7302024 | 0.83 | ACE (0.47) | ACEF2FKBP1APLGCASP1 | |
| SCHEMBL7297377 | 0.83 | F2 (0.50) | ACEF2FKBP1APRCPCTRB1 | |
| SCHEMBL7298681 | 0.80 | GAA (0.40) | ACEF2PLGCASP1FAP | |
| SCHEMBL7298055 | 0.79 | F2 (0.61) | F2PLGCASP1PRCPCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | claimed |