Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 10/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324515 | 0.92 | ACE (0.46) | ACEFKBP1AF2MTORFKBP4 | |
| SCHEMBL7304579 | 0.85 | SPHK2 (0.43) | ACEFKBP1AF2 | |
| SCHEMBL7303956 | 0.85 | CPT2 (0.42) | ACEF2 | |
| SCHEMBL7302024 | 0.82 | ACE (0.47) | ACEFKBP1AF2 | |
| Hydrochloric Acid SCHEMBL7303227 | 0.80 | ACE (0.41) | ACEFKBP1AF2MTORFKBP4 | |
| SCHEMBL7296963 | 0.78 | ACE (0.40) | ACEFKBP1A | |
| SCHEMBL7338057 | 0.78 | ACE (0.38) | ACEF2 | |
| SCHEMBL7298264 | 0.76 | ACE (0.45) | ACEF2 | |
| SCHEMBL7302798 | 0.76 | SPHK2 (0.44) | ACEFKBP1A | |
| SCHEMBL7297128 | 0.76 | CPT2 (0.44) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |