Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635862 | 0.77 | HPGD (0.58) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL31037128 | 0.77 | HPGD (0.58) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL7299430 | 0.71 | HPGD (0.70) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL18068458 | 0.71 | HPGD (0.56) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL29182281 | 0.71 | MEN1 (0.58) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL13300910 | 0.71 | MAPT (0.56) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL2407577 | 0.71 | HPGD (1.00) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL29640486 | 0.71 | HPGD (1.00) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL16107776 | 0.70 | TRPM4 (0.61) | MAPTHPGDHSD17B10ALOX15RECQL | |
| SCHEMBL3220975 | 0.68 | HPGD (0.58) | MAPTHPGDHSD17B10ALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |