Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301522 | 0.88 | MAPT (0.71) | HPGDHTTPPARGMAPTCYP1A2 | |
| SCHEMBL7304022 | 0.85 | HTT (0.67) | HPGDHTTPPARGMAPTNR1H4 | |
| SCHEMBL29960273 | 0.85 | MAPT (0.57) | HPGDHTTMAPTCYP1A2CYP2C9 | |
| SCHEMBL5789916 | 0.85 | MAPT (0.57) | HPGDHTTPPARGMAPTCYP1A2 | |
| SCHEMBL7297525 | 0.84 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19NR1H4 | |
| SCHEMBL5646672 | 0.84 | MAPT (0.56) | HPGDHTTMAPTCYP1A2CYP2C9 | |
| SCHEMBL6485998 | 0.83 | MAPT (0.77) | HPGDMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7293409 | 0.82 | SERPINE1 (0.67) | HPGDHTTPPARGMAPTNR1H4 | |
| SCHEMBL7295300 | 0.82 | HPGD (0.64) | HPGDHTTPPARGMAPTNR1H4 | |
| SCHEMBL7292289 | 0.82 | RAB9A (0.67) | HPGDPPARGMAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |