Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.68 |
| ▸ | ACACA | Q13085 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3505740 | 0.87 | ACACB (0.61) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL3504473 | 0.86 | ACACB (0.65) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL3505092 | 0.85 | L3MBTL1 (0.55) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL7295131 | 0.83 | ACACB (0.97) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL17233279 | 0.81 | ACACB (0.73) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL18598419 | 0.80 | ACACB (0.71) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL23588222 | 0.79 | ACACB (0.70) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL7302028 | 0.79 | ACACB (0.70) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL14339592 | 0.78 | NOTUM (0.64) | ACACBACACAL3MBTL1TDP1NPC1 | |
| SCHEMBL22280481 | 0.78 | PPARD (0.47) | ACACBACACAL3MBTL1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5356916-A | Treating Parkinson*s disease | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0504574-A1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-23 | — | — | EP | disclosed |