Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | HTR6 | P50406 | 7/20 | 0.59 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCH | P24723 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.50 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.50 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12486470 | 0.90 | KDM4E (0.69) | KDM4EHTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL7301825 | 0.81 | KDM4E (0.55) | KDM4EHTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL30906933 | 0.79 | KDM4E (0.86) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3399045 | 0.79 | KDM4E (0.86) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30906932 | 0.79 | KDM4E (0.86) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7301108 | 0.79 | KDM4E (0.56) | KDM4EHTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL7490360 | 0.78 | HTR3A (0.56) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2318444 | 0.78 | HTR3A (0.56) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3724622 | 0.78 | HTR3A (0.56) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3724624 | 0.78 | HTR3A (0.56) | KDM4EMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252570-A | Amidino and guanidino derivatives | B.I. ITALIA (IT) | 1993-10-12 | — | — | US | disclosed |
| US-5047410-A | Indolyl derivatives and their use as 5-HT3, receptor antagonists | ISTITUTO DE ANGELI S.P.A. (IT) | 1991-09-10 | — | — | US | disclosed |
| EP-0351385-A2 | New amidino and guanidino derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-01-17 | — | — | EP | disclosed |