Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.43 |
| ▸ | CTSS | P25774 | 10/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403757 | 1.00 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL3498485 | 0.87 | CYP2D6 (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL22502629 | 0.86 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL22502630 | 0.86 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL19974088 | 0.86 | CA1 (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2427380 | 0.86 | CA1 (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2401413 | 0.83 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9515168 | 0.83 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL10829329 | 0.83 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL27880264 | 0.83 | FOLH1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| CN-1091432-A | Can suppress the active peptide of hiv protease, its preparation with and medical use | SANKYO CO (JP) | 1994-08-31 | — | — | CN | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0217804-B1 | ANALOGS OF SUBSTANCES P | ENICHEM S.p.A. (IT) | 1991-10-02 | — | — | EP | disclosed |
| EP-0217804-A1 | ANALOGS OF SUBSTANCES P. | ENICHEM SPA (IT) | 1987-04-15 | — | — | EP | disclosed |
| EP-0156063-A2 | Hypoglycaemic tetrapeptides | Reichelt, Karl Ludvig (NO) | 1985-10-02 | — | — | EP | disclosed |