SCHEMBL1283871

SCHEMBL1283871

CC(C)(C)c1ccc(OCC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 1.00
EPHX2 P34913 1/20 0.68
NR1H4 Q96RI1 1/20 0.68
ALOX15 P16050 1/20 0.59
MCL1 Q07820 1/20 0.58
MEN1 O00255 1/20 0.57
RAB9A P51151 1/20 0.57
KMT2A Q03164 1/20 0.57
CYP2C19 P33261 2/20 0.57
NR4A2 P43354 1/20 0.57
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
POLB P06746 2/20 0.56
GAA P10253 1/20 0.56
HCAR2 Q8TDS4 1/20 0.55
ALDH1A1 P00352 2/20 0.55
LMNA P02545 1/20 0.54
MAPK1 P28482 1/20 0.54
FFAR1 O14842 1/20 0.53
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28429402 0.98 SMN1; SMN2 (0.96) SMN1; SMN2EPHX2NR1H4ALOX15MCL1
Hydrochloric Acid SCHEMBL4640626 0.98 SMN1; SMN2 (0.96) SMN1; SMN2EPHX2NR1H4ALOX15MCL1
Formaldehyde SCHEMBL28606744 0.96 SMN1; SMN2 (0.93) SMN1; SMN2EPHX2NR1H4ALOX15MCL1
SCHEMBL3389094 0.89 SMN1; SMN2 (0.79) SMN1; SMN2EPHX2NR1H4ALOX15MEN1
SCHEMBL1507692 0.89 SMN1; SMN2 (0.79) SMN1; SMN2EPHX2NR1H4ALOX15MCL1
SCHEMBL10647892 0.87 SMN1; SMN2 (0.76) SMN1; SMN2EPHX2NR1H4ALOX15MEN1
SCHEMBL7302398 0.85 SMN1; SMN2 (0.72) SMN1; SMN2EPHX2NR1H4MEN1RAB9A
SCHEMBL8219820 0.85 SMN1; SMN2 (0.73) SMN1; SMN2EPHX2NR1H4ALOX15MEN1
SCHEMBL5280680 0.84 SMN1; SMN2 (0.72) SMN1; SMN2EPHX2NR1H4ALOX15RAB9A
SCHEMBL339492 0.83 ALOX15 (0.81) SMN1; SMN2ALOX15MCL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108905-B Method for producing (Z) -trifluoromethaneenol ester by copper-catalyzed regioselective olefination and trifluoromethylation of carboxylic acid 湖南大学 2025-04-08 CN claimed
CN-116904764-A Method and device for selectively extracting lithium from lithium-containing alkaline aqueous solution 北京科技大学 2023-10-20 CN claimed
CN-116904765-A Method for selectively extracting, precipitating and enriching lithium from lithium-containing alkaline aqueous solution 北京科技大学 2023-10-20 CN claimed
CN-113493870-B Composite flocculant for ion type rare earth enrichment and enrichment method 福建省长汀金龙稀土有限公司 2023-04-07 CN claimed
CN-113493870-A Composite flocculant for ion type rare earth enrichment and enrichment method 厦门钨业股份有限公司 2021-10-12 CN claimed
CN-111417618-A Process for preparing enantiomerically and diastereomerically enriched cyclobutaneamines and cyclobutaneamides 先正达参股股份有限公司 2020-07-14 CN claimed
US-20130165446-A1 BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE HORIKOSHI, HIROYOSHI (CA) 2013-06-27 US claimed
EP-2581373-A1 BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE Fujita, Takashi (JP) 2013-04-17 EP claimed
JP-63041403-A None JP disclosed
US-12630497-B2 Compound having malate dehydrogenase inhibitory activity and pharmaceutical composition for preventing or treating cancer comprising same as active ingredient DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2026-05-19 US disclosed
US-20260083724-A1 COMPOUNDS TARGETING PAX3::FOXO1 FUSION PROTEIN GEORGETOWN UNIVERSITY (US) 2026-03-26 US disclosed
EP-3710422-B1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA CROP PROTECTION AG (CH) 2026-01-07 EP disclosed
CN-115108905-B Method for producing (Z) -trifluoromethaneenol ester by copper-catalyzed regioselective olefination and trifluoromethylation of carboxylic acid 湖南大学 2025-04-08 CN disclosed
CN-118146176-B GPR133/ADGRD1 agonist, preparation method and application thereof 山东大学 2024-11-15 CN disclosed
US-4310512-A Derivatives of acetic and propionic acids, compositions containing same and use as malodor counteractants BUSH BOAKE ALLEN INC. (US) 1982-01-12 US disclosed
US-4215009-A COMPLEXING ORONZIO DENORA IMPIANTI ELETTROCHIMICI S.P.A. (IT) 1980-07-29 US disclosed
US-4090862-A Novel phenoxycarboxylic acid aryloxy(thio)carbonylaminomethyl esters and their use for regulating plant growth BAYER AKTIENGESELLSCHAFT (DT) 1978-05-23 US disclosed
US-4013451-A 2-(SUBSTITUTED PHENOXY)PROPIONIC ACID PHILAGRO S.A. (FR) 1977-03-22 US disclosed
US-3980687-A Intermediates for the preparation of 17-substituted-Δ4 -gonenes ROUSSEL-UCLAF (FR) 1976-09-14 US disclosed
US-3975413-A Novel haptenes and antigens PIERDET ANDRE 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630497-B2 Compound having malate dehydrogenase inhibitory activity and pharmaceutical composition for preventing or treating cancer comprising same as active ingredient MDH2, MDH1, ME2 SMN1; SMN2 2420/4885EPHX2 3824/4885NR1H4 966/4885
US-20260083724-A1 COMPOUNDS TARGETING PAX3::FOXO1 FUSION PROTEIN PAX3, FOXO1, PAXBP1 SMN1; SMN2 48/4885EPHX2 4806/4885NR1H4 4658/4885
US-20130165446-A1 BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE PPARG, PPARA, PPARD SMN1; SMN2 4460/4885EPHX2 3143/4885NR1H4 109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.