Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 18/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 18/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319198 | 0.83 | PDE3B (0.56) | PDE3BPDE3AP2RY12MEN1PDE2A | |
| SCHEMBL1570572 | 0.82 | PDE3B (0.60) | PDE3BPDE3AP2RY12MEN1PDE2A | |
| Hydrochloric Acid SCHEMBL10605149 | 0.81 | PDE3B (0.58) | PDE3BPDE3AP2RY12MEN1PDE2A | |
| SCHEMBL11866311 | 0.81 | PDE3B (0.52) | PDE3BPDE3AP2RY12MEN1PDE2A | |
| SCHEMBL7306463 | 0.79 | PDE3B (0.70) | PDE3BPDE3AP2RY12MEN1PDE2A | |
| SCHEMBL4927003 | 0.79 | PDE3B (0.60) | PDE3BPDE3AP2RY12MEN1PDE2A | |
| SCHEMBL1570935 | 0.79 | PDE3B (0.60) | PDE3BPDE3AP2RY12MEN1PDE2A | |
| SCHEMBL7305770 | 0.77 | HTR3E (0.40) | MEN1KMT2ATIPARPLMNA | |
| SCHEMBL10377082 | 0.75 | PDE3B (0.59) | PDE3BPDE3AP2RY12MEN1PDE2A | |
| SCHEMBL10602377 | 0.75 | PDE3B (0.55) | PDE3BPDE3AP2RY12MEN1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31617-E | ANTICOAGULANTS; HYPOTENSIVE AND BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-3932407-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTICOAGULANTS | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |