Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302448 | 0.77 | PDE3B (0.56) | LMNATIPARPMEN1KMT2A | |
| SCHEMBL8969574 | 0.75 | ACHE (0.63) | DRD2DRD3LMNAMEN1KMT2A | |
| SCHEMBL8677159 | 0.69 | CYP1A2 (0.65) | MAPTTIPARP | |
| SCHEMBL4849552 | 0.62 | HTR3A (0.66) | HTR3EHTR3BADRB1DRD2CYP2C19 | |
| SCHEMBL22670012 | 0.62 | TAAR1 (0.36) | DRD2DRD3MAPTLMNANPC1 | |
| SCHEMBL30149392 | 0.62 | TAAR1 (0.36) | DRD2DRD3MAPTLMNANPC1 | |
| SCHEMBL8168688 | 0.62 | MAPT (0.46) | DRD2DRD3SIGMAR1MAPTMEN1 | |
| SCHEMBL10998253 | 0.61 | DRD2 (0.62) | HTR3EHTR3BADRB1DRD2CYP2C19 | |
| Hydrochloric Acid SCHEMBL10996275 | 0.60 | MAPT (0.63) | HTR3EHTR3BADRB1DRD2CYP2C19 | |
| SCHEMBL1026306 | 0.60 | CYP2C19 (0.57) | HTR3EHTR3BADRB1DRD2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31617-E | ANTICOAGULANTS; HYPOTENSIVE AND BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-3932407-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTICOAGULANTS | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |