Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352542 | 0.85 | TSHR (0.56) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11545681 | 0.82 | TSHR (0.41) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2200208 | 0.82 | TSHR (0.54) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8552268 | 0.80 | TSHR (0.55) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7305763 | 0.80 | TSHR (0.55) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13861497 | 0.80 | TSHR (0.42) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16654865 | 0.79 | TSHR (0.40) | TSHRALDH1A1GAAMAPT | |
| SCHEMBL31194577 | 0.79 | GAA (0.54) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8552869 | 0.78 | TSHR (0.52) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8553278 | 0.78 | TSHR (0.52) | TSHRMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719385-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | University of Vermont and State Agricultural College (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249380-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-12-05 | — | — | WO | disclosed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0636626-A1 | Pyrazolopyrimidine Derivatives | LABORATOIRES GLAXO SA (FR) | 1995-02-01 | — | — | EP | disclosed |