Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352542 | 0.84 | TSHR (0.56) | TSHRMAPTALDH1A1NR1I2AHR | |
| SCHEMBL11576859 | 0.82 | MAPT (0.54) | TSHRMAPTALDH1A1NR1I2AHR | |
| SCHEMBL2200208 | 0.81 | TSHR (0.54) | TSHRMAPTALDH1A1NR1I2AHR | |
| SCHEMBL7302490 | 0.80 | TSHR (0.59) | TSHRMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8553278 | 0.80 | TSHR (0.52) | TSHRMAPTALDH1A1NR1I2AHR | |
| SCHEMBL8552869 | 0.80 | TSHR (0.52) | TSHRMAPTALDH1A1NR1I2AHR | |
| SCHEMBL7305763 | 0.76 | TSHR (0.55) | TSHRMAPTALDH1A1NR1I2AHR | |
| SCHEMBL33720 | 0.76 | HTT (0.44) | MAPTALDH1A1NR1I2AHRBRD4 | |
| SCHEMBL12335146 | 0.76 | CYP1A2 (0.41) | MAPTALDH1A1NR1I2AHRBRD4 | |
| Hydrochloric Acid SCHEMBL6278290 | 0.74 | HTT (0.42) | MAPTALDH1A1NR1I2AHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |