Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.34 |
| ▸ | CTSC | P53634 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14432518 | 0.91 | CTSC (0.36) | HPGDEBPSIGMAR1L3MBTL1TSHR | |
| SCHEMBL5226414 | 0.91 | CTSC (0.36) | HPGDEBPSIGMAR1L3MBTL1TSHR | |
| SCHEMBL7310949 | 0.88 | L3MBTL1 (0.37) | HPGDEBPSIGMAR1L3MBTL1TSHR | |
| SCHEMBL5235546 | 0.83 | L3MBTL1 (0.39) | EBPSIGMAR1L3MBTL1TSHRCTSC | |
| SCHEMBL5232528 | 0.82 | KIF11 (0.37) | HPGDEBPSIGMAR1L3MBTL1CTSC | |
| SCHEMBL6013626 | 0.82 | KIF11 (0.37) | HPGDEBPSIGMAR1L3MBTL1CTSC | |
| SCHEMBL5232535 | 0.82 | KIF11 (0.37) | HPGDEBPSIGMAR1L3MBTL1CTSC | |
| SCHEMBL14432523 | 0.81 | CTSC (0.37) | HPGDL3MBTL1TSHRCTSCALDH1A1 | |
| SCHEMBL7304642 | 0.80 | EBP (0.54) | EBPSIGMAR1L3MBTL1TSHRGAA | |
| SCHEMBL5227717 | 0.80 | L3MBTL1 (0.39) | EBPSIGMAR1L3MBTL1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |