Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297525 | 0.87 | MAPT (0.69) | ALDH1A1RAB9ANPC1GLAATM | |
| SCHEMBL7292289 | 0.85 | RAB9A (0.67) | ALDH1A1RAB9ANPC1GLAATM | |
| SCHEMBL7301522 | 0.85 | MAPT (0.71) | ALDH1A1RAB9ANPC1GLAATM | |
| SCHEMBL14428130 | 0.85 | MAPT (0.57) | ALDH1A1RAB9ANPC1MAPTGAA | |
| SCHEMBL7297216 | 0.84 | CA1 (0.53) | ALDH1A1RAB9ANPC1GLAATM | |
| SCHEMBL7292413 | 0.84 | HSD17B2 (0.58) | ALDH1A1RAB9ANPC1GLAATM | |
| SCHEMBL28803930 | 0.83 | MAPT (0.52) | ALDH1A1RAB9ANPC1ATMCA1 | |
| SCHEMBL7302258 | 0.82 | HPGD (0.64) | ALDH1A1RAB9ANPC1GLAATM | |
| SCHEMBL5395767 | 0.82 | KMT2A (0.62) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL7291782 | 0.82 | MAPT (0.62) | ALDH1A1RAB9ANPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019233474-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2019-12-12 | — | — | WO | disclosed |
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |