Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | CPT2 | P23786 | 1/20 | 0.45 |
| ▸ | CPT1A | P50416 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304107 | 0.86 | CCR1 (0.49) | SCN4ARAB9AGHSRPKMHTT | |
| SCHEMBL13436116 | 0.85 | MEN1 (0.53) | SCN4ACTSCKMT2AMEN1GHSR | |
| Hydrochloric Acid SCHEMBL3980280 | 0.85 | CCR1 (0.48) | SCN4ARAB9AGHSRPKMHTT | |
| Hydrochloric Acid SCHEMBL3980274 | 0.85 | CCR1 (0.48) | SCN4ARAB9AGHSRPKMHTT | |
| SCHEMBL27394991 | 0.83 | SCN4A (0.48) | SCN4ACTSCKMT2AMEN1GHSR | |
| SCHEMBL9288424 | 0.83 | LMNA (0.51) | SCN4APOLBCTSCKMT2AMEN1 | |
| SCHEMBL7309838 | 0.83 | SCN4A (0.47) | SCN4APOLBCTSCKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11100316 | 0.83 | SCN4A (0.48) | SCN4ACTSCKMT2AMEN1HTR2C | |
| SCHEMBL14002159 | 0.83 | KMT2A (0.55) | SCN4ACTSCKMT2AMEN1GHSR | |
| SCHEMBL2092282 | 0.82 | SCN4A (0.47) | SCN4ACTSCKMT2AMEN1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |