Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13436116 | 0.85 | MEN1 (0.53) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL7302727 | 0.83 | SCN4A (0.53) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL9288424 | 0.81 | LMNA (0.51) | SCN4ACTSCMEN1KMT2AGHSR | |
| SCHEMBL27394991 | 0.81 | SCN4A (0.48) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL2092281 | 0.80 | SCN4A (0.47) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL7556633 | 0.80 | SCN4A (0.44) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL2092282 | 0.80 | SCN4A (0.47) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL13964105 | 0.79 | CTSC (0.51) | SCN4ACTSCHTR2CHTR2BMEN1 | |
| SCHEMBL9279932 | 0.79 | MEN1 (0.52) | SCN4ACTSCMEN1KMT2AGHSR | |
| SCHEMBL6970522 | 0.78 | POLB (0.43) | SCN4ACTSCHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |