Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302286 | 0.90 | ALDH1A1 (0.43) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL7297800 | 0.88 | ALDH1A1 (0.42) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7312820 | 0.83 | ALDH1A1 (0.49) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17020095 | 0.79 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL7303518 | 0.78 | CYP2D6 (0.46) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL17009637 | 0.77 | ALDH1A1 (0.41) | KDM4EALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL9808024 | 0.75 | KDM4E (0.59) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9808069 | 0.75 | KDM4E (0.55) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7302195 | 0.75 | PPARG (0.43) | ALDH1A1KMT2AMEN1RAB9AHTT | |
| SCHEMBL10916274 | 0.74 | KDM4E (0.59) | KDM4EHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |