Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 4/20 | 0.39 |
| ▸ | CTSC | P53634 | 4/20 | 0.38 |
| ▸ | F3 | P13726 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302891 | 1.00 | GLS (0.39) | GLSCTSCF3F2F10 | |
| SCHEMBL7292510 | 0.91 | CTSL (0.40) | CTSCMMECYP1A2LTA4H | |
| SCHEMBL7292514 | 0.91 | CTSL (0.40) | CTSCMMECYP1A2LTA4H | |
| SCHEMBL9012374 | 0.87 | CTSC (0.54) | CTSCCYP1A2CYP2D6 | |
| SCHEMBL6946752 | 0.87 | CTSC (0.54) | CTSCCYP1A2CYP2D6 | |
| SCHEMBL9012384 | 0.87 | CTSC (0.54) | CTSCCYP1A2CYP2D6 | |
| SCHEMBL6265071 | 0.87 | CTSC (0.54) | CTSCCYP1A2CYP2D6 | |
| SCHEMBL9438609 | 0.87 | CTSC (0.54) | CTSCCYP1A2CYP2D6 | |
| SCHEMBL7289470 | 0.86 | HDAC3 (0.40) | CTSCPOLBCPA1 | |
| SCHEMBL7289478 | 0.86 | HDAC3 (0.40) | CTSCPOLBCPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |